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BMCBI
2008
172views more  BMCBI 2008»
13 years 8 months ago
Compo: composite motif discovery using discrete models
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
Geir Kjetil Sandve, Osman Abul, Finn Drablø...
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
GC
2008
Springer
13 years 8 months ago
Laplacian Spectrum of Weakly Quasi-threshold Graphs
In this paper we study the class of weakly quasi-threshold graphs that are obtained from a vertex by recursively applying the operations (i) adding a new isolated vertex, (ii) addi...
R. B. Bapat, A. K. Lal, Sukanta Pati
BMCBI
2006
111views more  BMCBI 2006»
13 years 8 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
BMCBI
2006
108views more  BMCBI 2006»
13 years 8 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal