Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
We propose a new discriminative framework, namely Hidden Dynamic Conditional Random Fields (HDCRFs), for building probabilistic models which can capture both internal and external...
Obtaining an accurate multiple alignment of protein sequences is a difficult computational problem for which many heuristic techniques sacrifice optimality to achieve reasonable r...
- Our paper focuses on the generation of optimal test sequences and test cases using Intelligent Agents for highly reliable systems. Test sequences support test case generation for...
Long-range correlations in genomic base composition are a ubiquitous statistical feature among many eukaryotic genomes. In this article, these correlations are shown to substantia...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...