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» Comparison of Affymetrix GeneChip expression measures
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BIOINFORMATICS
2006
120views more  BIOINFORMATICS 2006»
13 years 7 months ago
Comparison of Affymetrix GeneChip expression measures
Motivation: In the Affymetrix GeneChip system, preprocessing occurs before one obtains expression level measurements. Because the number of competing preprocessing methods was lar...
Rafael A. Irizarry, Zhijin Wu, Harris A. Jaffee
BMCBI
2010
193views more  BMCBI 2010»
13 years 7 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
BMCBI
2007
104views more  BMCBI 2007»
13 years 7 months ago
A comparison of Affymetrix gene expression arrays
Background: Affymetrix GeneChips™ are an important tool in many facets of biological research. Recently, notable design changes to the chips have been made. In this study, we us...
Mark D. Robinson, Terence P. Speed
CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
14 years 15 days ago
A Learned Comparative Expression Measure for Affymetrix GeneChip DNA Microarrays
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...
BMCBI
2006
112views more  BMCBI 2006»
13 years 7 months ago
Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
Background: Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hy...
Lesley Jones, Darlene R. Goldstein, Gareth P. Hugh...