Background: There are many data mining methods but few comparisons between them. For example, there are at least two ways to build quality optimizers, programs that find project o...
Background: The expressed sequence tag (EST) methodology is an attractive option for the generation of sequence data for species for which no completely sequenced genome is availa...
Memetic algorithms with continuous local search methods have arisen as effective tools to address the difficulty of obtaining reliable solutions of high precision for complex cont...
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...