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FCCM
2009
IEEE
169views VLSI» more  FCCM 2009»
14 years 2 months ago
RC-BLASTn: Implementation and Evaluation of the BLASTn Scan Function
BLASTn is a tool universally used by biologists to identify similarities between nucleotide based biological genome sequences. This report describes an FPGA based hardware impleme...
Siddhartha Datta, Parag Beeraka, Ron Sass
PPSN
2004
Springer
14 years 24 days ago
LS-CMA-ES: A Second-Order Algorithm for Covariance Matrix Adaptation
Abstract. Evolution Strategies, Evolutionary Algorithms based on Gaussian mutation and deterministic selection, are today considered the best choice as far as parameter optimizatio...
Anne Auger, Marc Schoenauer, Nicolas Vanhaecke
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
GECCO
2005
Springer
129views Optimization» more  GECCO 2005»
14 years 1 months ago
Real-coded crossover as a role of kernel density estimation
This paper presents a kernel density estimation method by means of real-coded crossovers. Estimation of density algorithms (EDAs) are evolutionary optimization techniques, which d...
Jun Sakuma, Shigenobu Kobayashi
BMCBI
2007
144views more  BMCBI 2007»
13 years 7 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...