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» Comparisons of Protein Family Dynamics
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BMCBI
2007
175views more  BMCBI 2007»
13 years 8 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
BMCBI
2006
166views more  BMCBI 2006»
13 years 8 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2004
125views more  BMCBI 2004»
13 years 8 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
BMCBI
2008
163views more  BMCBI 2008»
13 years 8 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
FGCS
2007
107views more  FGCS 2007»
13 years 8 months ago
Algorithmic re-structuring and data replication for protein structure comparison on a GRID
This paper describes a major restructuring of PROuST, a method for protein structure comparison, for an efficient porting to the Grid. PROuST consists of different components: an...
Giovanni Ciriello, M. Comin, Concettina Guerra