Background: Over the past decade, a number of tools have emerged for the examination of homology relationships among protein sequences in a structural context. Most recent softwar...
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
Protein structural class describes the overall folding type of a protein or its domain. A number of methods were developed to predict protein structural class based on its primary...
Kanaka Durga Kedarisetti, Lukasz A. Kurgan, Scott ...
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...