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BMCBI
2010
224views more  BMCBI 2010»
15 years 4 months ago
An adaptive optimal ensemble classifier via bagging and rank aggregation with applications to high dimensional data
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...
Susmita Datta, Vasyl Pihur, Somnath Datta
BMCBI
2008
145views more  BMCBI 2008»
15 years 4 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2008
143views more  BMCBI 2008»
15 years 4 months ago
catmap: Case-control And TDT Meta-Analysis Package
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
Kristin K. Nicodemus
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BMCBI
2006
216views more  BMCBI 2006»
15 years 4 months ago
Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
ECCC
2006
145views more  ECCC 2006»
15 years 4 months ago
Constraint satisfaction: a personal perspective
Attempts at classifying computational problems as polynomial time solvable, NP-complete, or belonging to a higher level in the polynomial hierarchy, face the difficulty of undecid...
Tomás Feder