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BMCBI
2010
84views more  BMCBI 2010»
13 years 7 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
BMCBI
2010
127views more  BMCBI 2010»
13 years 7 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
ALIFE
2006
13 years 7 months ago
Picture This: The State of the Art in Visualization for Complex Adaptive Systems
Visualization has an increasingly important role to play in scientific research. Moreover, visualization has a special role to play within artificial life as a result of the inform...
Seth Bullock, Tom Smith, Jon Bird
BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
Demonstration of two novel methods for predicting functional siRNA efficiency
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...
Peilin Jia, Tieliu Shi, Yu-Dong Cai, Yixue Li
BMCBI
2007
59views more  BMCBI 2007»
13 years 7 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis