Background: Next-generation sequencing technologies have led to the high-throughput production of sequence data (reads) at low cost. However, these reads are significantly shorter...
Abstract. The intramolecular model for gene assembly in ciliates considers three operations, ld, hi, and dlad that can assemble any gene pattern through folding and recombination: ...
Tero Harju, Ion Petre, Vladimir Rogojin, Grzegorz ...
Background: Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can invol...
Sergey Koren, Jason R. Miller, Brian Walenz, Grang...
Signi cant advances have been made in the area of macro planning for assembly operations i.e., dividing a product into sub-assemblies, determining the sequence of assembly operati...
S. K. Gupta, Christiaan J. J. Paredis, P. F. Brown
We present an efficient, fully automated algorithm to assemble ESTs into full-length cDNA sequences that represent the complete coding regions of a gene. Our EST clustering algori...
Arthur Grossman, Charles Hauser, Hilary J. Holz, J...