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BIB
2008
93views more  BIB 2008»
13 years 9 months ago
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
Rainer Breitling, David Gilbert, Monika Heiner, Ri...
ICIC
2009
Springer
13 years 7 months ago
Inference of Differential Equation Models by Multi Expression Programming for Gene Regulatory Networks
This paper presents an evolutionary method for identifying the gene regulatory network from the observed time series data of gene expression using a system of ordinary differential...
Bin Yang, Yuehui Chen, Qingfang Meng
BMCBI
2006
116views more  BMCBI 2006»
13 years 9 months ago
Gene annotation and network inference by phylogenetic profiling
Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
Jie Wu, Zhenjun Hu, Charles DeLisi
CMSB
2006
Springer
14 years 1 months ago
Randomization and Feedback Properties of Directed Graphs Inspired by Gene Networks
Having in mind the large-scale analysis of gene regulatory networks, we review a graph decimation algorithm, called "leaf-removal", which can be used to evaluate the feed...
M. Cosentino Lagomarsino, P. Jona, B. Bassetti
RECOMB
2005
Springer
14 years 10 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur