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BMCBI
2006
239views more  BMCBI 2006»
13 years 8 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
101views more  BMCBI 2006»
13 years 8 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
BMCBI
2006
156views more  BMCBI 2006»
13 years 8 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...
BMCBI
2006
137views more  BMCBI 2006»
13 years 8 months ago
Cell_motility: a cross-platform, open source application for the study of cell motion paths
Background: Migration is an important aspect of cellular behaviour and is therefore widely studied in cell biology. Numerous components are known to participate in this process in...
Lennart Martens, Geert Monsieur, Christophe Ampe, ...
BMCBI
2006
114views more  BMCBI 2006»
13 years 8 months ago
BLISS: biding site level identification of shared signal-modules in DNA regulatory sequences
Background: Regulatory modules are segments of the DNA that control particular aspects of gene expression. Their identification is therefore of great importance to the field of mo...
Hailong Meng, Arunava Banerjee, Lei Zhou