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JCC
2007
82views more  JCC 2007»
13 years 7 months ago
Peptide reagent design based on physical and chemical properties of amino acid residues
: It has tremendous values for both drug discovery and basic research to develop a solid bioinformatical tool for guiding peptide reagent design. Based on the physical and chemical...
Qishi Du, Ri-Bo Huang, Yu-Tuo Wei, Cheng-Hua Wang,...
BMCBI
2007
96views more  BMCBI 2007»
13 years 7 months ago
Protein subcellular localization prediction based on compartment-specific features and structure conservation
Motivation: Protein subcellular localization is crucial for genome annotation, protein function prediction, and drug discovery. However, since determining subcellular localization...
Emily Chia-Yu Su, Hua-Sheng Chiu, Allan Lo, Jenn-K...
GECCO
2003
Springer
165views Optimization» more  GECCO 2003»
14 years 27 days ago
An Evolutionary Approach for Molecular Docking
We have developed an evolutionary approach for the flexible docking that is now an important component of a rational drug design. This automatic docking tool, referred to as the G...
Jinn-Moon Yang
AAAI
1990
13 years 8 months ago
A Design Based Approach to Constructing Computational Solutions to Diagnostic Problems
Troubleshooting problems in real manufacturing environments impose constraints on admissible solutions that make the computational solutions offered by "troubleshooting from ...
D. Volovik, Imran A. Zualkernan, Paul E. Johnson, ...
AAAI
2010
13 years 9 months ago
Computationally Feasible Automated Mechanism Design: General Approach and Case Studies
In many multiagent settings, a decision must be made based on the preferences of multiple agents, and agents may lie about their preferences if this is to their benefit. In mechan...
Mingyu Guo, Vincent Conitzer