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BMCBI
2006
94views more  BMCBI 2006»
15 years 4 months ago
Simulation of microarray data with realistic characteristics
Background: Microarray technologies have become common tools in biological research. As a result, a need for effective computational methods for data analysis has emerged. Numerou...
Matti Nykter, Tommi Aho, Miika Ahdesmäki, Pek...
PACT
2007
Springer
15 years 10 months ago
A Stochastic Semantics for BioAmbients
We consider BioAmbients, a calculus for specifying biological entities and for simulating and analysing their behaviour. We extend BioAmbients to take quantitative information into...
Linda Brodo, Pierpaolo Degano, Corrado Priami
ALMOB
2008
95views more  ALMOB 2008»
15 years 4 months ago
A stitch in time: Efficient computation of genomic DNA melting bubbles
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Eivind Tøstesen
BMCBI
2007
148views more  BMCBI 2007»
15 years 4 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2005
122views more  BMCBI 2005»
15 years 4 months ago
Computational verification of protein-protein interactions by orthologous co-expression
Background: High-throughput methods identify an overwhelming number of protein-protein interactions. However, the limited accuracy of these methods results in the false identifica...
Itay Tirosh, Naama Barkai