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RECOMB
2005
Springer
16 years 5 months ago
Graph Theoretical Insights into Evolution of Multidomain Proteins
We study properties of multidomain proteins from a graph theoretical perspective. In particular, we demonstrate connections between properties of the domain overlap graph and certa...
Teresa M. Przytycka, George Davis, Nan Song, Danni...
139
Voted
RECOMB
2005
Springer
16 years 5 months ago
Stability of Rearrangement Measures in the Comparison of Genome Sequences
We present data-analytic and statistical tools for studying rates of rearrangement of whole genomes and to assess the stability of these methods with changes in the level of resol...
David Sankoff, Matthew Mazowita
155
Voted
RECOMB
2005
Springer
16 years 5 months ago
The Pathalyzer: A Tool for Analysis of Signal Transduction Pathways
Abstract. The Pathalyzer is a program for analyzing large-scale signal transduction networks. Reactions and their substrates and products are represented as transitions and places ...
David L. Dill, Merrill Knapp, Pamela Gage, Carolyn...
136
Voted
RECOMB
2004
Springer
16 years 5 months ago
Multiple organism gene finding by collapsed gibbs sampling
The Gibbs sampling method has been widely used for sequence analysis after it was successfully applied to the problem of identifying regulatory motif sequences upstream of genes. ...
Sourav Chatterji, Lior Pachter
RECOMB
2004
Springer
16 years 5 months ago
Somatic evolution of cancer
We study a situation that arises in the somatic evolution of cancer. Consider a finite population of replicating cells and a sequence of mutations: type 0 can mutate to type 1, wh...
Martin Nowak