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    BMCBI
    2007
    116views more  BMCBI 2007»
    Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
    13 years 8 months ago
    Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
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    Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
    César L. Avila, Viviana A. Rapisarda, Ricar...
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    BMCBI
    2007
    115views more  BMCBI 2007»
    Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
    13 years 8 months ago
    Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
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    Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
    Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
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    JACM
    2006
    99views more  JACM 2006»
    Finding a maximum likelihood tree is hard
    13 years 8 months ago
    Finding a maximum likelihood tree is hard
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    Abstract. Maximum likelihood (ML) is an increasingly popular optimality criterion for selecting evolutionary trees [Felsenstein 1981]. Finding optimal ML trees appears to be a very...
    Benny Chor, Tamir Tuller
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    JCB
    2006
    107views more  JCB 2006»
    Maximum Likelihood Molecular Clock Comb: Analytic Solutions
    13 years 8 months ago
    Maximum Likelihood Molecular Clock Comb: Analytic Solutions
    Download  research.haifa.ac.il
    Maximum likelihood (ML) is increasingly used as an optimality criterion for selecting evolutionary trees, but finding the global optimum is a hard computational task. Because no g...
    Benny Chor, Amit Khetan, Sagi Snir
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    EOR
    2007
    100views more  EOR 2007»
    Parallel radial basis function methods for the global optimization of expensive functions
    13 years 8 months ago
    Parallel radial basis function methods for the global optimization of expensive functions
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    We introduce a master–worker framework for parallel global optimization of computationally expensive functions using response surface models. In particular, we parallelize two r...
    Rommel G. Regis, Christine A. Shoemaker
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