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» Computational analyses of eukaryotic promoters
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RECOMB
2005
Springer
14 years 10 months ago
Likely Scenarios of Intron Evolution
Whether common ancestors of eukaryotes and prokaryotes had introns is one of the oldest unanswered questions in molecular evolution. Recently completed genome sequences have been u...
Miklós Csürös
RECOMB
2005
Springer
14 years 10 months ago
A Partial Solution to the C-Value Paradox
In the half-century since the C-value paradox (the apparent lack of correlation between organismal genome size and morphological complexity) was described, there have been no expli...
Jeffrey M. Marcus
BMCBI
2007
96views more  BMCBI 2007»
13 years 9 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
BMCBI
2006
75views more  BMCBI 2006»
13 years 9 months ago
A machine learning strategy to identify candidate binding sites in human protein-coding sequence
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
Thomas Down, Bernard Leong, Tim J. P. Hubbard
BMCBI
2008
169views more  BMCBI 2008»
13 years 10 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...