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BMCBI
2010
189views more  BMCBI 2010»
13 years 9 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
BMCBI
2007
97views more  BMCBI 2007»
13 years 9 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
BMCBI
2007
114views more  BMCBI 2007»
13 years 9 months ago
Probabilistic prediction and ranking of human protein-protein interactions
Background: Although the prediction of protein-protein interactions has been extensively investigated for yeast, few such datasets exist for the far larger proteome in human. Furt...
Michelle S. Scott, Geoffrey J. Barton
BMCBI
2010
113views more  BMCBI 2010»
13 years 9 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
BMCBI
2007
176views more  BMCBI 2007»
13 years 9 months ago
Genome Expression Pathway Analysis Tool - Analysis and visualization of microarray gene expression data under genomic, proteomic
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...
Markus Weniger, Julia C. Engelmann, Jörg Schu...
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