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PLDI
2010
ACM
14 years 2 months ago
Finding low-utility data structures
Many opportunities for easy, big-win, program optimizations are missed by compilers. This is especially true in highly layered Java applications. Often at the heart of these misse...
Guoqing Xu, Nick Mitchell, Matthew Arnold, Atanas ...
ICGA
1997
122views Optimization» more  ICGA 1997»
13 years 11 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
BMCBI
2010
113views more  BMCBI 2010»
13 years 9 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
DAC
2007
ACM
14 years 10 months ago
A New Twisted Differential Line Structure in Global Bus Design
Twisted differential line structure can effectively reduce crosstalk noise on global bus, which foresees a wide applicability. However, measured performance based on fabricated ci...
Zhanyuan Jiang, Shiyan Hu, Weiping Shi
DAC
2004
ACM
14 years 10 months ago
A frequency relaxation approach for analog/RF system-level simulation
The increasing complexity of today's mixed-signal integrated circuits necessitates both top-down and bottom-up system-level verification. Time-domain state-space modeling and...
Xin Li, Yang Xu, Peng Li, Padmini Gopalakrishnan, ...