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CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Inverse Design of Large Molecules using Linear Diophantine Equations
We have previously developed a method [1] for the inverse design of small ligands. This method can be used to design novel compounds with optimized properties (such as drugs) and ...
Shawn Martin, W. Michael Brown, Jean-Loup Faulon, ...
DAM
2006
78views more  DAM 2006»
13 years 8 months ago
Hybrid rounding techniques for knapsack problems
We address the classical knapsack problem and a variant in which an upper bound is imposed on the number of items that can be selected. We show that appropriate combinations of ro...
Monaldo Mastrolilli, Marcus Hutter
FOCS
2002
IEEE
14 years 1 months ago
Low-Dimensional Linear Programming with Violations
Two decades ago, Megiddo and Dyer showed that linear programming in two and three dimensions (and subsequently any constant number of dimensions) can be solved in linear time. In ...
Timothy M. Chan
ISQED
2008
IEEE
153views Hardware» more  ISQED 2008»
14 years 2 months ago
Accelerating Clock Mesh Simulation Using Matrix-Level Macromodels and Dynamic Time Step Rounding
Clock meshes have found increasingly wide applications in today’s high-performance IC designs. The inherent routing redundancies associated with clock meshes lead to improved cl...
Xiaoji Ye, Min Zhao, Rajendran Panda, Peng Li, Jia...
WAOA
2005
Springer
92views Algorithms» more  WAOA 2005»
14 years 1 months ago
Rounding of Sequences and Matrices, with Applications
Abstract. We show that any real matrix can be rounded to an integer matrix in such a way that the rounding errors of all row sums are less than one, and the rounding errors of all ...
Benjamin Doerr, Tobias Friedrich, Christian Klein,...