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» Computing a Center-Transversal Line
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BMCBI
2010
84views more  BMCBI 2010»
13 years 8 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2008
155views more  BMCBI 2008»
13 years 8 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BMCBI
2007
179views more  BMCBI 2007»
13 years 8 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
BMCBI
2008
123views more  BMCBI 2008»
13 years 8 months ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...
CGF
2010
144views more  CGF 2010»
13 years 8 months ago
Illustrative White Matter Fiber Bundles
Diffusion Tensor Imaging (DTI) has made feasible the visualization of the fibrous structure of the brain white matter. In the last decades, several fiber-tracking methods have bee...
Ron Otten, Anna Vilanova, Huub van De Wetering