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BMCBI
2006
103views more  BMCBI 2006»
13 years 10 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2006
150views more  BMCBI 2006»
13 years 10 months ago
Cluster analysis of protein array results via similarity of Gene Ontology annotation
Background: With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to t...
Cheryl Wolting, C. Jane McGlade, David Tritchler
BMCBI
2006
94views more  BMCBI 2006»
13 years 10 months ago
Genepi: a blackboard framework for genome annotation
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Stéphane Descorps-Declère, Danielle ...
EOR
2006
148views more  EOR 2006»
13 years 10 months ago
Pareto ant colony optimization with ILP preprocessing in multiobjective project portfolio selection
One of the most important, common and critical management issues lies in determining the "best" project portfolio out of a given set of investment proposals. As this dec...
Karl F. Doerner, Walter J. Gutjahr, Richard F. Har...
BMCBI
2007
116views more  BMCBI 2007»
13 years 10 months ago
Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
César L. Avila, Viviana A. Rapisarda, Ricar...
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