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BMCBI
2008
202views more  BMCBI 2008»
13 years 8 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
RECOMB
2007
Springer
14 years 8 months ago
Comparative Analysis of Spatial Patterns of Gene Expression in Drosophila melanogaster Imaginal Discs
Determining the precise spatial extent of expression of genes across different tissues, along with knowledge of the biochemical function of the genes is critical for understanding ...
Cyrus L. Harmon, Parvez Ahammad, Ann Hammonds, Ric...
BMCBI
2011
13 years 3 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
14 years 3 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
GECCO
2007
Springer
162views Optimization» more  GECCO 2007»
14 years 2 months ago
A multi-objective approach to discover biclusters in microarray data
The main motivation for using a multi–objective evolutionary algorithm for finding biclusters in gene expression data is motivated by the fact that when looking for biclusters ...
Federico Divina, Jesús S. Aguilar-Ruiz