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CP
2003
Springer
14 years 1 months ago
A SAT-Based Approach to Multiple Sequence Alignment
Multiple sequence alignment is a central problem in Bioinformatics. A known integer programming approach is to apply branch-and-cut to exponentially large graph-theoretic models. T...
Steven David Prestwich, Desmond G. Higgins, Orla O...
BMCBI
2002
108views more  BMCBI 2002»
13 years 8 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
KDD
2009
ACM
239views Data Mining» more  KDD 2009»
14 years 9 months ago
Tell me something I don't know: randomization strategies for iterative data mining
There is a wide variety of data mining methods available, and it is generally useful in exploratory data analysis to use many different methods for the same dataset. This, however...
Heikki Mannila, Kai Puolamäki, Markus Ojala, ...
BMCBI
2006
114views more  BMCBI 2006»
13 years 8 months ago
A high level interface to SCOP and ASTRAL implemented in Python
Background: Benchmarking algorithms in structural bioinformatics often involves the construction of datasets of proteins with given sequence and structural properties. The SCOP da...
James A. Casbon, Gavin E. Crooks, Mansoor A. S. Sa...
ISSA
2004
13 years 10 months ago
A Framework For Monitoring Insider Misuse Of It Applications
Many security incidents involve legitimate users who misuse their existing privileges, such that they have the system-level right to perform an action, but not the moral or ethica...
Aung Htike Phyo