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BMCBI
2008
102views more  BMCBI 2008»
13 years 10 months ago
Monitoring the evolutionary aspect of the Gene Ontology to enhance predictability and usability
Background: Much effort is currently made to develop the Gene Ontology (GO). Due to the dynamic nature of information it addresses, GO undergoes constant updates whose results are...
Jong C. Park, Tak-eun Kim, Jinah Park
CORR
2008
Springer
118views Education» more  CORR 2008»
13 years 9 months ago
Distributed Constrained Optimization with Semicoordinate Transformations
Recent work has shown how information theory extends conventional full-rationality game theory to allow bounded rational agents. The associated mathematical framework can be used ...
William G. Macready, David Wolpert
BMCBI
2006
126views more  BMCBI 2006»
13 years 9 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
BMCBI
2006
89views more  BMCBI 2006»
13 years 9 months ago
ORENZA: a web resource for studying ORphan ENZyme activities
Background: Despite the current availability of several hundreds of thousands of amino acid sequences, more than 36% of the enzyme activities (EC numbers) defined by the Nomenclat...
Olivier Lespinet, Bernard Labedan
BMCBI
2006
100views more  BMCBI 2006»
13 years 9 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight