Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
We propose a functional mixture model for simultaneous clustering and alignment of sets of curves measured on a discrete time grid. The model is specifically tailored to gene exp...
Darya Chudova, Christopher E. Hart, Eric Mjolsness...
The biological interpretation of large-scale gene expression data is one of the challenges in current bioinformatics. The state-of-theart approach is to perform clustering and then...
Italo Zoppis, Daniele Merico, Marco Antoniotti, Bu...
Abstract—In this paper we demonstrate the inherent robustness of minimum distance estimator that makes it a potentially powerful tool for parameter estimation in gene expression ...
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...