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BMCBI
2007
134views more  BMCBI 2007»
13 years 7 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
NIPS
2003
13 years 8 months ago
Gene Expression Clustering with Functional Mixture Models
We propose a functional mixture model for simultaneous clustering and alignment of sets of curves measured on a discrete time grid. The model is specifically tailored to gene exp...
Darya Chudova, Christopher E. Hart, Eric Mjolsness...
ISBRA
2007
Springer
14 years 1 months ago
Discovering Relations Among GO-Annotated Clusters by Graph Kernel Methods
The biological interpretation of large-scale gene expression data is one of the challenges in current bioinformatics. The state-of-theart approach is to perform clustering and then...
Italo Zoppis, Daniele Merico, Marco Antoniotti, Bu...
BIBE
2007
IEEE
155views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Partial Mixture Model for Tight Clustering in Exploratory Gene Expression Analysis
Abstract—In this paper we demonstrate the inherent robustness of minimum distance estimator that makes it a potentially powerful tool for parameter estimation in gene expression ...
Yinyin Yuan, Chang-Tsun Li
BMCBI
2008
126views more  BMCBI 2008»
13 years 7 months ago
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...