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BMCBI
2006
118views more  BMCBI 2006»
13 years 7 months ago
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
QSIC
2005
IEEE
14 years 1 months ago
Ontology Based Requirements Analysis: Lightweight Semantic Processing Approach
We propose a software requirements analysis method based on domain ontology technique, where we can establish a mapping between a software requirements specification and the doma...
Haruhiko Kaiya, Motoshi Saeki
NAR
2010
184views more  NAR 2010»
13 years 2 months ago
RegPrecise: a database of curated genomic inferences of transcriptional regulatory interactions in prokaryotes
The RegPrecise database (http://regprecise.lbl.gov) was developed for capturing, visualization and analysis of predicted transcription factor regulons in prokaryotes that were rec...
Pavel S. Novichkov, Olga N. Laikova, Elena S. Novi...
BMCBI
2010
121views more  BMCBI 2010»
13 years 7 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
RSCTC
2000
Springer
197views Fuzzy Logic» more  RSCTC 2000»
13 years 11 months ago
Rough Set Approach to CBR
We discuss how Case Based Reasoning (CBR) (see e.g. [1], [4]) philosophy of adaptation of some known situations to new similar ones can be realized in rough set framework [5] for c...
Jan Wierzbicki