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» Conserved RNA Pseudoknots
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BMCBI
2008
162views more  BMCBI 2008»
13 years 7 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois
BMCBI
2006
60views more  BMCBI 2006»
13 years 7 months ago
Use of a multi-way method to analyze the amino acid composition of a conserved group of orthologous proteins in prokaryotes
Background: Amino acids in proteins are not used equally. Some of the differences in the amino acid composition of proteins are between species (mainly due to nucleotide compositi...
Alberto Pasamontes, Santiago Garcia-Vallvé
BMCBI
2007
183views more  BMCBI 2007»
13 years 7 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
BMCBI
2004
126views more  BMCBI 2004»
13 years 7 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes