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    BMCBI
    2007
    146views more  BMCBI 2007»
    PubMed related articles: a probabilistic topic-based model for content similarity
    13 years 11 months ago
    PubMed related articles: a probabilistic topic-based model for content similarity
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    Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
    Jimmy J. Lin, W. John Wilbur
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    BMCBI
    2008
    122views more  BMCBI 2008»
    High-throughput bioinformatics with the Cyrille2 pipeline system
    13 years 11 months ago
    High-throughput bioinformatics with the Cyrille2 pipeline system
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    Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
    Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
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    BMCBI
    2007
    83views more  BMCBI 2007»
    Identification of sequence motifs significantly associated with antisense activity
    13 years 11 months ago
    Identification of sequence motifs significantly associated with antisense activity
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    Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
    Kyle A. McQuisten, Andrew S. Peek
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    BMCBI
    2008
    135views more  BMCBI 2008»
    Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
    13 years 11 months ago
    Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
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    Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
    Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
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    BMCBI
    2008
    162views more  BMCBI 2008»
    Background correction using dinucleotide affinities improves the performance of GCRMA
    13 years 11 months ago
    Background correction using dinucleotide affinities improves the performance of GCRMA
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    Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
    Raad Z. Gharaibeh, Anthony Fodor, Cynthia Gibas
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