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» Constraint Based Methods for Biological Sequence Analysis
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BMCBI
2011
14 years 11 months ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
BMCBI
2008
99views more  BMCBI 2008»
15 years 4 months ago
A new real-time PCR method to overcome significant quantitative inaccuracy due to slight amplification inhibition
Background: Real-time PCR analysis is a sensitive DNA quantification technique that has recently gained considerable attention in biotechnology, microbiology and molecular diagnos...
Michele Guescini, Davide Sisti, Marco B. L. Rocchi...
ASPDAC
2009
ACM
130views Hardware» more  ASPDAC 2009»
15 years 10 months ago
Analog placement with common centroid and 1-D symmetry constraints
— 1In this paper, we will present a placement method for analog circuits. We consider both common centroid and 1-D symmetry constraints, which are the two most common types of pl...
Linfu Xiao, Evangeline F. Y. Young
BMCBI
2005
106views more  BMCBI 2005»
15 years 4 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
DILS
2007
Springer
15 years 5 months ago
A High-Throughput Bioinformatics Platform for Mass Spectrometry-Based Proteomics
The success of mass spectrometry-based proteomics in emerging applications such as biomarker discovery and clinical diagnostics, is predicated substantially on its ability to achie...
Thodoros Topaloglou, Moyez Dharsee, Rob M. Ewing, ...