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» Constraint Based Methods for Biological Sequence Analysis
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BMCBI
2010
123views more  BMCBI 2010»
15 years 4 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
BMCBI
2007
113views more  BMCBI 2007»
15 years 4 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BMCBI
2007
131views more  BMCBI 2007»
15 years 4 months ago
Prediction of peptides observable by mass spectrometry applied at the experimental set level
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
William S. Sanders, Susan M. Bridges, Fiona M. McC...
IPMI
2007
Springer
16 years 5 months ago
Adaptive Time-Frequency Models for Single-Trial M/EEG Analysis
Abstract. A new method is introduced for estimating single-trial magnetoor electro-encephalography (M/EEG), based on a non-linear fit of timefrequency atoms. The method can be appl...
Christian Bénar, Maureen Clerc, Théo...
BMCBI
2008
144views more  BMCBI 2008»
15 years 4 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath