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» Constraint Based Methods for Biological Sequence Analysis
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SDM
2009
SIAM
111views Data Mining» more  SDM 2009»
16 years 18 days ago
A New Constraint for Mining Sets in Sequences.
Discovering interesting patterns in event sequences is a popular task in the field of data mining. Most existing methods try to do this based on some measure of cohesion to deter...
Bart Goethals, Boris Cule, Céline Robardet
122
Voted
RECOMB
2002
Springer
16 years 3 months ago
Approximate matching of secondary structures
This talk presents an algorithm to search for all approximate matches of a helix in a genome, where a helix is a combination of sequence and folding constraints. It is a joint wor...
Nadia El-Mabrouk, Mathieu Raffinot
162
Voted
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
15 years 1 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
BMCBI
2006
102views more  BMCBI 2006»
15 years 3 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
161
Voted
BMCBI
2006
203views more  BMCBI 2006»
15 years 3 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...