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» Constraint Based Methods for Biological Sequence Analysis
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BIOINFORMATICS
2007
74views more  BIOINFORMATICS 2007»
15 years 4 months ago
Simultaneous alignment and annotation of cis-regulatory regions
Genomic transcriptional processes rely heavily on the combinatorial binding of transcription factors on the upstream regions of genes. Analysis and complete characterization of su...
Abha Singh Bais, Steffen Grossmann, Martin Vingron
BIBE
2001
IEEE
15 years 7 months ago
Gene Classification using Expression Profiles: A Feasibility Study
As various genome sequencing projects have already been completed or are near completion, genome researchers are shifting their focus from structural genomics to functional genomi...
Michihiro Kuramochi, George Karypis
149
Voted
BMCBI
2010
89views more  BMCBI 2010»
15 years 4 months ago
Predictors of natively unfolded proteins: unanimous consensus score to detect a twilight zone between order and disorder in gene
Background: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-functio...
Antonio Deiana, Andrea Giansanti
116
Voted
BMCBI
2010
240views more  BMCBI 2010»
15 years 4 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...
BMCBI
2007
179views more  BMCBI 2007»
15 years 3 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...