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» Constraint Based Methods for Biological Sequence Analysis
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155
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BMCBI
2010
155views more  BMCBI 2010»
15 years 26 days ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
141
Voted
ISMB
1996
15 years 4 months ago
Compact Encoding Strategies for DNA Sequence Similarity Search
Determining whether two DNA sequences are similar is an essential component of DNA sequence analysis. Dynamic programming is the algorithm of choice if computational time is not t...
David J. States, Pankaj Agarwal
139
Voted
KDD
2001
ACM
163views Data Mining» more  KDD 2001»
16 years 3 months ago
Learning to recognize brain specific proteins based on low-level features from on-line prediction servers
During the last decade, the area of bioinformatics has produced an overwhelming amount of data, with the recently published draft of the human genome being the most prominent exam...
Henrik Boström, Joakim Cöster, Lars Aske...
105
Voted
BMCBI
2008
77views more  BMCBI 2008»
15 years 3 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
140
Voted
BIOINFORMATICS
2011
14 years 7 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...