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» Constraint Based Methods for Biological Sequence Analysis
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143
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SP
2008
IEEE
122views Security Privacy» more  SP 2008»
15 years 3 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...
159
Voted
BMCBI
2010
143views more  BMCBI 2010»
15 years 3 months ago
Shape based kinetic outlier detection in real-time PCR
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
Davide Sisti, Michele Guescini, Marco B. L. Rocchi...
113
Voted
BMCBI
2006
129views more  BMCBI 2006»
15 years 3 months ago
A literature-based similarity metric for biological processes
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
122
Voted
IDEAL
2007
Springer
15 years 9 months ago
Methods to Bicluster Validation and Comparison in Microarray Data
There are lots of validation indexes and techniques to study clustering results. Biclustering algorithms have been applied in Systems Biology, principally in DNA Microarray analysi...
Rodrigo Santamaría, Luis Quintales, Roberto...
156
Voted
BMCBI
2007
148views more  BMCBI 2007»
15 years 3 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...