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BMCBI
2006
133views more  BMCBI 2006»
13 years 10 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
BMCBI
2006
115views more  BMCBI 2006»
13 years 10 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
BMCBI
2006
116views more  BMCBI 2006»
13 years 10 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
CJ
2006
84views more  CJ 2006»
13 years 10 months ago
Instruction Level Parallelism through Microthreading - A Scalable Approach to Chip Multiprocessors
Most microprocessor chips today use an out-of-order instruction execution mechanism. This mechanism allows superscalar processors to extract reasonably high levels of instruction ...
Kostas Bousias, Nabil Hasasneh, Chris R. Jesshope
BMCBI
2007
164views more  BMCBI 2007»
13 years 9 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason