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    BMCBI
    2010
    151views more  BMCBI 2010»
    Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
    13 years 7 months ago
    Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
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    Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
    Zhanchao Li, Xuan Zhou, Zong Dai, Xiaoyong Zou
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    BMCBI
    2010
    109views more  BMCBI 2010»
    Pripper: prediction of caspase cleavage sites from whole proteomes
    13 years 7 months ago
    Pripper: prediction of caspase cleavage sites from whole proteomes
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    Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
    Mirva Piippo, Niina Lietzén, Olli Nevalaine...
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    BMCBI
    2010
    109views more  BMCBI 2010»
    Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
    13 years 7 months ago
    Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
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    Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
    Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
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    BMCBI
    2010
    240views more  BMCBI 2010»
    CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
    13 years 7 months ago
    CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
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    Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
    Olivier Friard, Angela Re, Daniela Taverna, Michel...
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    BMCBI
    2007
    173views more  BMCBI 2007»
    Ringo - an R/Bioconductor package for analyzing ChIP-chip readouts
    13 years 7 months ago
    Ringo - an R/Bioconductor package for analyzing ChIP-chip readouts
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    Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is a high-throughput assay for DNA-protein-binding or post-translational chromatin/histone modi...
    Joern Toedling, Oleg Sklyar, Tammo Krueger, Jenny ...
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