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BIBE
2003
IEEE
121views Bioinformatics» more  BIBE 2003»
14 years 1 months ago
Time Series Analysis of Gene Expression and Location Data
We develop a method for integrating time series expression profiles and factor-gene binding data to quantify dynamic aspects of gene regulation. We estimate latencies for transcr...
Chen-Hsiang Yeang, Tommi Jaakkola
IJCNN
2008
IEEE
14 years 2 months ago
Comparative study on normalization procedures for cluster analysis of gene expression datasets
—Normalization before clustering is often needed for proximity indices, such as Euclidian distance, which are sensitive to differences in the magnitude or scales of the attribute...
Marcílio Carlos Pereira de Souto, Daniel S....
BMCBI
2008
127views more  BMCBI 2008»
13 years 7 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
ITA
2006
167views Communications» more  ITA 2006»
13 years 7 months ago
Characterization of lung tumor subtypes through gene expression cluster validity assessment
The problem of assessing the reliability of clusters patients identified by clustering algorithms is crucial to estimate the significance of subclasses of diseases detectable at b...
Giorgio Valentini, Francesca Ruffino
SDM
2007
SIAM
98views Data Mining» more  SDM 2007»
13 years 9 months ago
Lattice based Clustering of Temporal Gene-Expression Matrices
Individuals show different cell classes when they are in the different stages of a disease, have different disease subtypes, or have different response to a treatment or envir...
Yang Huang, Martin Farach-Colton