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» Contextual alignment of biological sequences
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BMCBI
2007
128views more  BMCBI 2007»
13 years 7 months ago
Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assess
Background: Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. Howeve...
Paolo Ferragina, Raffaele Giancarlo, Valentina Gre...
ISMB
1996
13 years 9 months ago
Parameterization Studies for the SAM and HMMER Methods of Hidden Markov Model Generation
Multiple sequence alignment of distantly related viral proteins remains a challenge to all currently available alignment methods. The hidden Markovmodel approach offers a new,flex...
Marcella A. McClure, Chris Smith, Pete Elton
DKE
2008
91views more  DKE 2008»
13 years 7 months ago
SUSAX: Context-specific searching in XML documents using sequence alignment techniques
Keyword searching while very successful in narrowing down the contents of the Web to the pertaining subset of information, has two primary drawbacks. First, the accuracy of the se...
Kajal T. Claypool
BMCBI
2005
123views more  BMCBI 2005»
13 years 7 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas
BIOCOMP
2007
13 years 9 months ago
Quality-Based Similarity Search for Biological Sequence Databases
Low-Complexity Regions (LCRs) of biological sequences are the main source of false positives in similarity searches for biological sequence databases. We consider the problem of ï...
Xuehui Li, Tamer Kahveci