309 search results - page 57 / 62 » Contextual alignment of biological sequences |
BMCBI
2007
13 years 7 months ago
2007
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
BMCBI
2011
13 years 2 months ago
2011
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
BMCBI
2008
13 years 7 months ago
2008
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
BMCBI
2006
13 years 7 months ago
2006
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
BMCBI
2010
13 years 7 months ago
2010
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...