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    BMCBI
    2010
    87views more  BMCBI 2010»
    Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
    13 years 11 months ago
    Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
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    Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
    Jessica L. Larson, Guo-Cheng Yuan
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    BMCBI
    2007
    169views more  BMCBI 2007»
    Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
    13 years 11 months ago
    Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
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    Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
    Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
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    BMCBI
    2008
    104views more  BMCBI 2008»
    ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
    13 years 11 months ago
    ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
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    Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
    Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
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    BMCBI
    2008
    107views more  BMCBI 2008»
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
    13 years 11 months ago
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
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    Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
    Juan R. González, Josep L. Carrasco, Llu&ia...
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    BMCBI
    2008
    121views more  BMCBI 2008»
    Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
    13 years 11 months ago
    Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
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    Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
    Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
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