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BMCBI
2006
89views more  BMCBI 2006»
13 years 10 months ago
A joint model for nonparametric functional mapping of longitudinal trajectory and time-to-event
Background: The characterization of the relationship between a longitudinal response process and a time-to-event has been a pressing challenge in biostatistical research. This has...
Min Lin, Rongling Wu
BMCBI
2006
82views more  BMCBI 2006»
13 years 10 months ago
Transcriptomic response to differentiation induction
Background: Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A com...
G. W. Patton, Robert M. Stephens, I. A. Sidorov, X...
BMCBI
2006
87views more  BMCBI 2006»
13 years 10 months ago
Prediction of indirect interactions in proteins
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
Peteris Prusis, Staffan Uhlén, Ramona Petro...
BMCBI
2006
86views more  BMCBI 2006»
13 years 10 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2006
97views more  BMCBI 2006»
13 years 10 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...