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» Correlation Analysis of the Shrinking Generator
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BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
JLIN: A java based linkage disequilibrium plotter
Background: A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disea...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
BMCBI
2006
99views more  BMCBI 2006»
13 years 7 months ago
Genetic algorithm learning as a robust approach to RNA editing site prediction
Background: RNA editing is one of several post-transcriptional modifications that may contribute to organismal complexity in the face of limited gene complement in a genome. One f...
James Thompson, Shuba Gopal
BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
Comparative assessment of performance and genome dependence among phylogenetic profiling methods
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
Evan S. Snitkin, Adam M. Gustafson, Joseph C. Mell...
BMCBI
2007
179views more  BMCBI 2007»
13 years 7 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...