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ALMOB
2008
81views more  ALMOB 2008»
13 years 7 months ago
Stability of multiple alignments and phylogenetic trees: an analysis of ABC-transporter proteins family
Background: Sequence-based phylogeny reconstruction is a fundamental task in Bioinformatics. Practically all methods for phylogeny reconstruction are based on multiple alignments....
Holger Wagner, Burkhard Morgenstern, Andreas W. M....
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Protein docking by Rotation-Based Uniform Sampling (RotBUS) with fast computing of intermolecular contact distance and residue d
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Albert Solernou, Juan Fernández-Recio
BMCBI
2010
106views more  BMCBI 2010»
13 years 7 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li
BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
BMCBI
2010
172views more  BMCBI 2010»
13 years 7 months ago
Inferring gene regression networks with model trees
Background: Novel strategies are required in order to handle the huge amount of data produced by microarray technologies. To infer gene regulatory networks, the first step is to f...
Isabel A. Nepomuceno-Chamorro, Jesús S. Agu...