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BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2005
143views more  BMCBI 2005»
13 years 7 months ago
Gene capture prediction and overlap estimation in EST sequencing from one or multiple libraries
Background: In expressed sequence tag (EST) sequencing, we are often interested in how many genes we can capture in an EST sample of a targeted size. This information provides ins...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, Liying Cui...
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
ISBI
2004
IEEE
14 years 8 months ago
4D Image Warping for Measurement of Longitudinal Brain Changes
This paper presents a method for robustly measuring temporal morphological brain changes, by means of a 4D image warping mechanism. Longitudinal stability is achieved by consideri...
Dinggang Shen
BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
Probabilistic annotation of protein sequences based on functional classifications
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...