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BMCBI
2011
12 years 11 months ago
Protein alignment algorithms with an efficient backtracking routine on multiple GPUs
Background: Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for seque...
Jacek Blazewicz, Wojciech Frohmberg, Michal Kierzy...
BMCBI
2011
12 years 11 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
BMCBI
2011
12 years 11 months ago
MINE: Module Identification in NEtworks
Background: Graphical models of network associations are useful for both visualizing and integrating multiple types of association data. Identifying modules, or groups of function...
Kahn Rhrissorrakrai, Kristin C. Gunsalus
BMCBI
2011
12 years 11 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
BMCBI
2011
12 years 11 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
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