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136
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BMCBI
2008
102views more  BMCBI 2008»
15 years 3 months ago
Response projected clustering for direct association with physiological and clinical response data
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
Sung-Gon Yi, Taesung Park, Jae K. Lee
BMCBI
2007
153views more  BMCBI 2007»
15 years 3 months ago
MPHASYS: a mouse phenotype analysis system
Background: Systematic, high-throughput studies of mouse phenotypes have been hampered by the inability to analyze individual animal data from a multitude of sources in an integra...
R. Brent Calder, Rudolf B. Beems, Harry van Steeg,...
BMCBI
2008
129views more  BMCBI 2008»
15 years 3 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
140
Voted
BMCBI
2008
148views more  BMCBI 2008»
15 years 3 months ago
Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements
Background: Liquid chromatography coupled to mass spectrometry (LC-MS) has become a prominent tool for the analysis of complex proteomics and metabolomics samples. In many applica...
Eva Lange, Ralf Tautenhahn, Steffen Neumann, Cleme...
141
Voted
BMCBI
2008
135views more  BMCBI 2008»
15 years 3 months ago
Facilitating the development of controlled vocabularies for metabolomics technologies with text mining
Background: Many bioinformatics applications rely on controlled vocabularies or ontologies to consistently interpret and seamlessly integrate information scattered across public r...
Irena Spasic, Daniel Schober, Susanna-Assunta Sans...
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