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» Current approaches to gene regulatory network modelling
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BIOWIRE
2007
Springer
14 years 27 days ago
Evolutionary and Temporal Dynamics of Transcriptional Regulatory Networks
Transcriptional regulation is a key mechanism that allows cells to make the appropriate amount of proteins at the right time. This is mediated by transcription factors that respond...
M. Madan Babu
RECOMB
2004
Springer
14 years 7 months ago
Learning Regulatory Network Models that Represent Regulator States and Roles
Abstract. We present an approach to inferring probabilistic models of generegulatory networks that is intended to provide a more mechanistic representation of transcriptional regul...
Keith Noto, Mark Craven
CEC
2003
IEEE
13 years 10 months ago
Dynamics of gene expression in an artificial genome
Abstract- Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulator...
Kai Willadsen, Janet Wiles
BMCBI
2006
144views more  BMCBI 2006»
13 years 6 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
COMPLEXITY
2010
173views more  COMPLEXITY 2010»
13 years 1 months ago
Signal-regulated systems and networks
The paper presents the use of signal regulatory networks, a biologically-inspired model based on gene regulatory networks. Signal regulatory networks are a way of understanding a ...
Terence L. van Zyl, Elizabeth Marie Ehlers