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» Current approaches to gene regulatory network modelling
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GLVLSI
2003
IEEE
175views VLSI» more  GLVLSI 2003»
14 years 19 days ago
A custom FPGA for the simulation of gene regulatory networks
We present a unique FPGA that uses a mix of digital and large-signal analog computation for the simulation of gene regulatory networks. The prototype IC consists of a 4x5 array of...
Ilias Tagkopoulos, Charles A. Zukowski, German Cav...
HYBRID
2007
Springer
14 years 1 months ago
Model Checking Genetic Regulatory Networks with Parameter Uncertainty
The lack of precise numerical information for the values of biological parameters severely limits the development and analysis of models of genetic regulatory networks. To deal wit...
Grégory Batt, Calin Belta, Ron Weiss
EUROGP
2006
Springer
140views Optimization» more  EUROGP 2006»
13 years 11 months ago
Evolving Noisy Oscillatory Dynamics in Genetic Regulatory Networks
We introduce a genetic programming (GP) approach for evolving genetic networks that demonstrate desired dynamics when simulated as a discrete stochastic process. Our representation...
André Leier, P. Dwight Kuo, Wolfgang Banzha...
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 8 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...