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» Current approaches to gene regulatory network modelling
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BMCBI
2011
13 years 17 hour ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf
APBC
2004
116views Bioinformatics» more  APBC 2004»
13 years 9 months ago
Evolving Genetic Regulatory Networks Using an Artificial Genome
Boolean models of genetic regulatory networks (GRNs) have been shown to exhibit many of the characteristic dynamics of real GRNs, with gene expression patterns settling to point a...
Jennifer Hallinan, Janet Wiles
ENTCS
2007
96views more  ENTCS 2007»
13 years 8 months ago
Semantics of Biological Regulatory Networks
The aim of the paper is to revisit the model of Biological Regulatory Networks (BRN) which was proposed by René Thomas to model the interactions between a set of genes. We give a...
Gilles Bernot, Franck Cassez, Jean-Paul Comet, Fra...
ISMB
1997
13 years 9 months ago
Functional Prediction of B. subtilis Genes from Their Regulatory Sequences
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Tetsushi Yada, Yasushi Totoki, Takahiro Ishii, Ken...
CIBCB
2009
IEEE
13 years 9 months ago
Steady-state analysis of genetic regulatory networks modeled by nonlinear ordinary differential equations
Although Ordinary Differential Equations (ODEs) have been used to model Genetic Regulatory Networks (GRNs) in many previous works, their steady-state behaviors are not well studied...
Haixin Wang, Lijun Qian, Edward R. Dougherty